A novel community driven software for functional enrichment analysis of extracellular vesicles data

By Mohashin Pathan, Shivakumar Keerthikumar, David Chisanga, R. Alessandro, C. Ang, P. Askenase, Arsen O. Batagov, A. Benito‐Martin, G. Camussi, Aled Clayton and 37 more. Journal of Extracellular Vesicles, 2017

339 citations recorded by the source corpus.

ABSTRACT Bioinformatics tools are imperative for the in depth analysis of heterogeneous high-throughput data. Most of the software tools are developed by specific laboratories or groups or companies wherein they are designed to perform the required analysis for the group. However, such software tools may fail to capture “what the community needs in a tool”. Here, we describe a novel community-driven approach to build a comprehensive functional enrichment analysis tool. Using the existing FunRich tool as a template, we invited researchers to request additional features and/or changes. Remarkably, with the enthusiastic participation of the community, we were able to implement 90% of the requested features. FunRich enables plugin for extracellular vesicles wherein users can download and analyse data from Vesiclepedia database. By involving researchers early through community needs software development, we believe that comprehensive analysis tools can be developed in various scientific disciplines.

Subfields: Molecular Biology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/7937e01ad9d6aa5c61ce997ae9063f96653a73c4

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

  1. Suresh Mathivanan
  2. C. Théry
  3. Richard J. Simpson
  4. Hina Kalra

Citations in the corpus