NF-κB p50-deficient mice show reduced anxiety-like behaviors in tests of exploratory drive and anxiety

By C. Kassed, M. Herkenham. 2004

105 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Transcription Factors in Long-Term Memory and Synaptic Plasticity (2009, unknown): “Thus, whereas NF B knockout mice have impaired radial maze memory, c-Rel knock-out mice have normal fear conditioning memory; intact memory is also generally found in mice lacking the p50 NF B subunit (119, 120, 137).”
NF-κB/Rel Regulates Inhibitory and Excitatory Neuronal Function and Synaptic Plasticity (2006, background): “Similarly, mice lacking the p50 subunit of NF-B/Rel display impaired emotional learning and decreased anxiety-related responses but exhibit increased exploratory activity ( 37 , 38).”
Impaired Adult Neurogenesis Associated with Short-Term Memory Defects in NF-κB p50-Deficient Mice (2008, background): “As previously described (Kassed and Herkenham, 2004), p50 / mice showed increased exploratory behavior compared with wt animals.”