Single neurons in prefrontal cortex encode abstract rules

By Jonathan D. Wallis, K. C. Anderson, Earl K. Miller. Nature, 2001

1,079 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/78cc6655d62126c295c66719657d19e2560d4957

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In Cognitive Neuroscience

Citations in the corpus

Consensus Paper: The Cerebellum's Role in Movement and Cognition (2013, background): “…posterior parietal areas to the cerebellum provide compelling evidence that the cerebellum processes information beyond the motor domain, from areas concerned with higher cognitive functions (e.g., implementing rules that govern actions rather than the kinematic details of motor control [40 – 42]).”
Abstract context representations in primate amygdala and prefrontal cortex (2015, background): “The PFC has been shown to encode rules and other abstract information (Buckley et al., 2009; Durstewitz et al., 2010; Salzman and Fusi, 2010; Stokes et al., 2013; Wallis et al., 2001).”
Prefrontal Cell Activities Related to Monkeys' Success and Failure in Adapting to Rule Changes in a Wisconsin Card Sorting Test Analog (2006, methodology): “In the tasks used in previous single-cell recording studies (Sakagami and Niki, 1994; White and Wise, 1999; Asaad et al., 2000; Wallis et al., 2001), the monkeys were informed of the required task or rule in each trial by an explicit cue or by differences in configurations of trials.”
Integration of cognitive and motivational context information in the primate prefrontal cortex. (2007, background): “Cognitive context-representing neuronal activities (showing differential precue baseline activities) have also been reported in LPFC in multitask situations (Asaad et al. 2000; Wallis et al. 2001) and in the Wisconsin card sorting test analog (Mansouri et al. 2006).”
Hierarchically organized behavior and its neural foundations: A reinforcement-learning perspective (2008, neutral): “Here, a single pattern of DLPFC activation serves to represent an entire mapping from stimuli to responses, i.e., a policy (Asaad, Rainer, & Miller, 2000; Bunge, 2004; Hoshi, Shima, & Tanji, 1998; Johnston & Everling, 2006; Rougier, Noell, Braver, Cohen, & O’Reilly, 2005; Shimamura, 2000; Wallis, A”
Neuroimaging studies of shifting attention: a meta-analysis (2004, background): “…was expected based on previous research (e.g., Cutrell and Marrocco, 2002; Davidson and Marrocco, 2000), but evidence for prefrontal involvement was weaker than expected based on findings of DLPFC involvement in cognitive control (Asaad et al., 2000; Miller and Cohen, 2001; Wallis et al., 2001).”
Orbitofrontal cortex and its contribution to decision-making. (2007, background): “Yet when one records the activity of OFC neurons during the performance of working memory tasks, their activity can closely resemble that of lateral PFC neurons (Wallis et al. 2001).”
The geometry of abstraction in hippocampus and prefrontal cortex (2020, background): “Neurons in ACC and DLPFC have been shown to encode rules and other cognitive information (Wallis et al., 2001;Miller et al., 2003; Buckley et al., 2009; Antzoulatos and Miller, 2011; Wutz et al., 2018; Saez et al., 2015), but testing whether a neural ensemble of single units represents one or more v”
An adaptive coding model of neural function in prefrontal cortex (2001, background): “In a successive same–different matching task, with trial-by-trial cues indicating whether the monkey should respond to matches or mismatches, Wallis et al.(28) showed similar rule (match versus mismatch) and object selectivity across dorsolateral, ventrolateral and orbital surfaces, but again with s”
Cortical Information Flow During Flexible Sensorimotor Decisions (2015, positive): “Neuronal activity encodes task rules in prefrontal (6, 8, 14, 15), parietal (2), and visual (16) cortices.”