The roles of TGFβ in the tumour microenvironment

By Michael W. Pickup, Sergey Novitskiy, H. Moses. Nature Reviews. Cancer, 2013

833 citations recorded by the source corpus.

The influence of the microenvironment on tumour progression is becoming clearer. In this Review we address the role of an essential signalling pathway, that of transforming growth factor-β, in the regulation of components of the tumour microenvironment and how this contributes to tumour progression.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/783a2f6b052f1781bf797e9196233809ed714e10

Citations in the corpus

• Revisiting the hallmarks of cancer. (2017, neutral): “But just to demonstrate how components of the TME integrate with other hallmarks we select the cancer-associated fibroblasts.”