Antibiotic resistance-the need for global solutions.
By Ramanan Laxminarayan, Adriano Duse, C. Wattal, Anita K M Zaidi, H. Wertheim, Nithima Sumpradit, E. Vlieghe, G. L. Hara, I. Gould, H. Goossens and 16 more. Lancet. Infectious Diseases (Print), 2013
827 citations recorded by the source corpus.
The causes of antibiotic resistance are complex and include human behaviour at many levels of society; the consequences affect everybody in the world. Similarities with climate change are evident. Many efforts have been made to describe the many different facets of antibiotic resistance and the interventions needed to meet the challenge. However, coordinated action is largely absent, especially at the political level, both nationally and internationally. Antibiotics paved the way for unprecedented medical and societal developments, and are today indispensible in all health systems. Achievements in modern medicine, such as major surgery, organ transplantation, treatment of preterm babies, and cancer chemotherapy, which we today take for granted, would not be possible without access to effective treatment for bacterial infections. Within just a few years, we might be faced with dire setbacks, medically, socially, and economically, unless real and unprecedented global coordinated actions are immediately taken. Here, we describe the global situation of antibiotic resistance, its major causes and consequences, and identify key areas in which action is urgently needed.
Subfields: Applied Microbiology and Biotechnology, Molecular Medicine, Pharmacology
View Paper: https://www.semanticscholar.org/paper/782a0632afcaaeaf6974e1f1181f9dacb9dcfc1d
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Citations in the corpus
- Antimicrobial resistance in humans, livestock and the wider environment (2015, neutral): “The result is that in Europe, the volume of agricultural usage of antibiotics continues to rival that of medical usage and in the USA (which recently introduced a voluntary ban on growth promoters), agricultural usage exceeds medical usage [15].”
- Antimicrobial peptides: Application informed by evolution (2020, background): “Against the backdrop of accelerating antibiotic resistance (69, 70), antimicrobial peptides hold promise for use in clinical and veterinary settings.”