Maternal Infection Requiring Hospitalization During Pregnancy and Autism Spectrum Disorders

By H. Atladóttir, P. Thorsen, L. Østergaard, D. Schendel, S. Lemcke, M. Abdallah, E. Parner. Journal of Autism and Developmental Disorders, 2010

881 citations recorded by the source corpus.

Subfields: Obstetrics and Gynecology, Psychiatry and Mental health, Speech and Hearing

View Paper: https://www.semanticscholar.org/paper/78024da3baf1b920639cd07191acb8c1e649c607

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Citations in the corpus

Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism (2011, background): “Nongenetic risk factors that may index environmental influences include parental age,(24) low birth weight,(25) multiple births,(26) and maternal infections during pregnancy.(27) Future studies that seek to elucidate such factors and their role in enhancing or suppressing genetic susceptibility are ”
Autism risk factors: genes, environment, and gene-environment interactions (2012, result): “The identification of summer birth as a risk factor is consistent with the results of a recent study showing that maternal infection in the first trimester increases autism risk.(84) Overall, preterm birth was not associated with the risk of autism.”
High intelligence: A risk factor for psychological and physiological overexcitabilities (2018, background): “Similarly, maternal infection in the first and second trimester and the subsequent significant immune activation, increases autism risk (Atladóttir et al., 2010) and maternal immune activation is an environmental trigger, which has been demonstrated in the lab to induce autism-like behavioral defect”
The role of immune dysfunction in the pathophysiology of autism (2011, neutral): “…hospitalization for a viral infection in the first trimester of pregnancy, or mothers hospitalized for a bacterial infection in the second trimester of pregnancy (Atladottir et al., 2010), suggesting that bacterial and viral infections may confer different risks depending on gestational age.”
The microbiota modulates gut physiology and behavioral abnormalities associated with autism (2013, neutral): “We utilize thematernal immune activation (MIA) model, which is based on large epidemiological studies linking maternal infection to increased autism risk in the offspring (Atladóttir et al., 2010; Gorrindo et al., 2012).”