Emerging pathogenic links between microbiota and the gut–lung axis

By K. Budden, S. Gellatly, David L A Wood, M. Cooper, M. Morrison, Philip Hugenholtz, P. Hansbro. Nature Reviews Microbiology, 2016

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Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System (2020, background): “10, 63, 65, 66 There is broad support for these observations in pulmonary diseases including PH, COPD, and asthma 67, 68 and in type 2 diabetes mellitus where dysbiosis characterized by decreased microbial richness and diversity, altered representation of bacterial metabolic pathways and modificatio”
Ten questions concerning the built environment and mental health (2019, background): “Recent research has also developed a microbiome-lung-brain model with bidirectional signaling [118], either directly to the brain or indirectly through the gut [119].”
Clinical Characteristics of COVID-19 Patients With Digestive Symptoms in Hubei, China: A Descriptive, Cross-Sectional, Multicenter Study (2020, background): “The effect is called the “gut-lung axis” (20,21), which may further explain why patients with COVID-19 pneumonia often have digestive symptoms.”
Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis (2020, background): “Although viral infections can change the microbiome, the latter also is involved in adaptive immune responses against respiratory pathogens [187,188], triggering immune reactions of the innate system [189].”