Caloric restriction.

By J. Speakman, S. Mitchell. Molecular Aspects of Medicine, 2011

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Autophagy and aging. (2011, background): “(Insulin/IGF-1 receptor) loss-of-function mutant in C. elegans Enhanced autophagy and life span Abolishment of longevity phenotype in animals with loss-of-function mutations of bec-1 or upon atg-7 or atg-12 RNAi Melendez et al., 2003 Dietary restriction mutant eat-2 (ad1113) in C. elegans.”
Impact of intermittent fasting on health and disease processes (2016, neutral): “Otherwise, we will not review studies of CR which are much more numerous than studies of IF, and have been reviewed elsewhere recently (Speakman and Mitchell, 2011; Mercken et al., 2012; Longo et al., 2015).”
Guidelines for Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children and Adolescents: Growth Hormone Deficiency, Idiopathic Short Stature, and Primary Insulin-Like Growth Factor-I Deficiency (2016, background): “Reduction in IGF-I via caloric restriction induces apoptosis and prevents or slows tumor growth [132].”