Ensemble dynamics of hippocampal regions CA3 and CA1.

By John Guzowski, James J. Knierim, Edvard I. Moser. Neuron, 2004

371 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/77262dff39440a37c5657ed8ce9dc36b9e612d65

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Network dynamics underlying the formation of sparse, informative representations in the hippocampus (2008, positive): “We do know that although both CA3 and CA1 show place specific activity, these areas differ in their responses to new or altered environments (Guzowski et al., 2004; Lee et al., 2004a,b; Leutgeb et al., 2004; Alvernhe et al., 2008).”
Progressive transformation of hippocampal neuronal representations in "morphed" environments. (2005, background): “Indirect evidence suggests that hippocampal assemblies perform both of these processes (Guzowski et al., 2004).”
Tracking the Flow of Hippocampal Computation: Pattern Separation, Pattern Completion, and Attractor Dynamics (2015, background): “Taken together with our double rotation data, these experiments suggest that CA3 displays the sigmoidal Δinput – Δoutput relationship predicted by theory (McClelland & Goddard, 1996; Rolls & Treves, 1998; Guzowski et al., 2004).”
Hippocampal mechanisms for the context-dependent retrieval of episodes (2005, positive): “This allows region CA3 activity to represent temporal context of events, consistent with the evidence of context-dependent firing of neurons in region CA3 ( Guzowski, Knierim, & Moser, 2004; Leutgeb, Leutgeb, Treves, Moser, & Moser, 2004), and for impairment of context-dependent behavior with selec”
CA3 Retrieves Coherent Representations from Degraded Input: Direct Evidence for CA3 Pattern Completion and Dentate Gyrus Pattern Separation (2014, background): “…collaterals in CA3 may produce attractor dynamics that result in pattern completion (or generalization) when input representations are similar to stored memories (attractor basins) or pattern separation when input representations are more distinct (Guzowski et al., 2004; Rolls and Treves, 1998).”
The Episodic Memory System: Neurocircuitry and Disorders (2009, positive): “Notably, this abnormality was selective to area CA3, the subfield of the hippocampus, which normally is inclined to strong pattern completion or separation (known as attractor dynamics) (Guzowski et al, 2004).”
Using immediate-early genes to map hippocampal subregional functions. (2007, background): “…environment (Guzowski et al. 2006) strongly resemble the characteristics of location-specific activity of hippocampal place cells, suggesting that neurons expressing Arc after exploration of an environment are place cells that expressed a firing field in that environment (Guzowski et al. 2004).”
Dissociating the past from the present in the activity of place cells (2006, background): “These processes are, in fact, reflected in the activity of CA3 pyramidal cells (Guzowski et al., 2004) and believed to be dependent on the CA3 associational circuit (Nakazawa et al.”