Position statement: Utility, limitations, and pitfalls in measuring testosterone: an Endocrine Society position statement.

By W. Rosner, R. Auchus, R. Azziz, P. Sluss, H. Raff. Journal of Clinical Endocrinology and Metabolism, 2007

1,184 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Molecular Biology, Reproductive Medicine

View Paper: https://www.semanticscholar.org/paper/76f4035a09ca52b9cde8784495d9a091a2f86605

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology, Diabetes and Metabolism

1. André Tchernof
2. J. Despres
3. R. Norman
4. D. Ehrmann
5. S. Grundy

In Molecular Biology

1. D. Ehrmann

In Reproductive Medicine

1. H. Escobar-Morreale
2. R. Norman
3. E. Diamanti-Kandarakis
4. D. Ehrmann
5. R. Legro
6. Didier Dewailly
7. R. Azziz
8. Bart C. J. M. Fauser

Citations in the corpus

• The polycystic ovary syndrome: a position statement from the European Society of Endocrinology. (2014, neutral): “The vast majority of laboratories performing a total serum testosterone assay use direct methods without extraction before performing an immunoassay (48, 49).”
• Pathophysiology of human visceral obesity: an update. (2013, background): “Again limitations in the measurement of androgen levels in women may possibly explain these discrepancies (470).”
• Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline. (2018, neutral): “culated from TT, SHBG, and albumin levels (23, 24).”
• Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. (2010, methodology): “Most of the circulating testosterone is bound to SHBG and to albumin (18, 19); only 0.”
• The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. (2009, background): “The present recommendation is to measure free T concentration either directly by equilibrium dialysis, or to calculate free T based on the total T measured accurately (e.g., by RIA using column chromatography, or by LC-MS or GC-MS) and SHBG (e.g., measured using competitive binding or a high quality”
• Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline (2013, methodology): “Given variability in T levels and the poor standardization of assays (31), it is difficult to define an absolute level that is diagnostic of PCOS or other causes of hyperandrogenism, and the Task Force recommends familiarity with local assays.”