Genome-Wide Patterns of Nucleotide Substitution Reveal Stringent Functional Constraints on the Protein Sequences of Thermophiles

By Robert Friedman, J. Drake, Austin L. Hughes. 2004

70 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

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Citations in the corpus

• Avoiding Dangerous Missense: Thermophiles Display Especially Low Mutation Rates (2009, background): “monotonically with the two thermophile values in bold, are 35– 36–37–38–41–50–50–51–68–69, providing no hint of a role for this variable, as also noted in the earlier molecular-evolution study [5].”