DNMT3A mutations in acute myeloid leukemia
By Mrinal Y. Shah, J. Licht. Nature Genetics, 2011
1,136 citations recorded by the source corpus.
Subfields: Genetics, Hematology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/76bae6d7d771b1873076924dea9b9c68ae195990
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Genetics
- S. Baylin
- Peter A. Jones
- C. López‐Otín
- Chuan He
- Grant A. Challen
- Richard K. Wilson
- Daniel C. Koboldt
- A. Young
In Hematology
- C. López‐Otín
- Grant A. Challen
- Peter A. Jones
- J. Dick
- A. Young
- S. Baylin
- Brenda M. Birmann
- T. Druley
In Molecular Biology
Citations in the corpus
- TET2 inactivation results in pleiotropic hematopoietic abnormalities in mouse and is a recurrent event during human lymphomagenesis. (2011, neutral): “Viable bone marrow cells were available only at the AML phase.”
- METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification (2017, background): “Importantly, our data suggest that, just like in DNA methylation, in which mutations of either DNMT3A or TET proteins can contribute to AML development (Delhommeau et al., 2009; Ley et al., 2010), the imbalance of RNA m(6)A methylation through aberrant expressions of either writer or eraser could ti”
- Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults (2016, positive): “Despite its prevalence, clonal haematopoiesis shares many mutations with AML, raising additional questions regarding the sequence of mutation acquisition and cooperating events necessary for malignant transformation.”
- SomaticSniper: identification of somatic point mutations in whole genome sequencing data (2012, methodology): “Availability and implementation: Binaries are freely available for download at http://gmt.genome.wustl.edu/somatic-sniper/current/, implemented in C and supported on Linux and Mac OS X. Contact: delarson@wustl.edu; lding@wustl.edu Supplementary information: Supplementary data are available at Bioinf”
- Landscape of somatic mutations and clonal evolution in mantle cell lymphoma (2013, background): “2 per Mb), slightly higher to CLL (26) or acute myeloid leukemia (27), but lower than in other lymphoid or nonhematopoietic tumors (28, 29).”