Functional ultrasound imaging of the brain
By Emilie Macé, Gabriel Montaldo, Ivan Cohen, M. Baulac, Mathias Fink, Mickaël Tanter. Nature Methods, 2011
697 citations recorded by the source corpus.
We present functional ultrasound (fUS), a method for imaging transient changes in blood volume in the whole brain at better spatiotemporal resolution than with other functional brain imaging modalities. fUS uses plane-wave illumination at high frame rate and can measure blood volumes in smaller vessels than previous ultrasound methods. fUS identifies regions of brain activation and was used to image whisker-evoked cortical and thalamic responses and the propagation of epileptiform seizures in the rat brain.
Subfields: Biomedical Engineering, Radiology, Nuclear Medicine and Imaging
View Paper: https://www.semanticscholar.org/paper/768d14246c65f9c60a2710762441b3a29bb1b2f7
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In Biomedical Engineering
In Radiology, Nuclear Medicine and Imaging
Citations in the corpus
- Modern Diagnostic Imaging Technique Applications and Risk Factors in the Medical Field: A Review (2022, background): “Functional ultrasound can detect the brain’s active portion [98].”
- Ultrasound Imaging Velocimetry: a review (2016, background): “Nevertheless, the excellent temporal resolution makes Power Doppler suitable for so-called functional imaging: it can visualise changes in blood flow patterns, e.g. in the brain as a result of external stimuli (Macé et al. 2011).”
- Adaptive Spatiotemporal SVD Clutter Filtering for Ultrafast Doppler Imaging Using Similarity of Spatial Singular Vectors (2018, background): “This increased sensitivity lead to numerous clinical application, for example in cardiac imaging [3] or liver vascular imaging [4], but also opened a whole new playground in fundamental research with functional imaging [5]–[7] and preclinical applications [8], [9].”
- Ultrasound Localization Microscopy and Super-Resolution: A State of the Art (2018, neutral): “It opened an entirely new field with functional ultrasound [23], [24], which can map the neuronal brain activation of free-moving”