Nanoscale size effect of magnetic nanocrystals and their utilization for cancer diagnosis via magnetic resonance imaging.

By Young-wook Jun, Yong-Min Huh, Jin-sil Choi, Jae‐Hyun Lee, Ho-Taek Song, Sungjun Kim, Sarah Yoon, Kyung-sup Kim, Jeon-Soo Shin, J. Suh and 1 more. Journal of the American Chemical Society, 2005

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Since the use of magnetic nanocrystals as probes for biomedical system is attractive, it is important to develop optimal synthetic protocols for high-quality magnetic nanocrystals and to have the systematic understanding of their nanoscale properties. Here we present the development of a synthetically controlled magnetic nanocrystal model system that correlates the nanoscale tunabilities in terms of size, magnetism, and induced nuclear spin relaxation processes. This system further led to the development of high-performance nanocrystal-antibody probe systems for the diagnosis of breast cancer cells via magnetic resonance imaging.

Subfields: Biomaterials, Biomedical Engineering, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/758d6ce411d4c9b8cf780b3de3c4d6733b02e130

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In Biomaterials

  1. Challa S. S. R. Kumar
  2. Gang Bao
  3. Sulin Zhang
  4. Faruq Mohammad
  5. S. Anand
  6. Huajian Gao
  7. M. Mohapatra
  8. S. Laurent

In Biomedical Engineering

  1. Challa S. S. R. Kumar
  2. Gang Bao
  3. Isaac Koh
  4. S. Sant
  5. Faruq Mohammad
  6. S. Anand
  7. Huajian Gao
  8. M. Mohapatra

In Molecular Biology

  1. Challa S. S. R. Kumar
  2. Gang Bao
  3. Faruq Mohammad
  4. S. Laurent
  5. Lee Josephson
  6. M. Mahmoudi

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