Cardiac excitation–contraction coupling
By Donald M. Bers. Nature, 2002
4,830 citations recorded by the source corpus.
Subfields: Cardiology and Cardiovascular Medicine, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/751753b1380d829f7b90f84b3e72a5721bd74774
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In Cardiology and Cardiovascular Medicine
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- Wei Zhan
- Thomas L. Gallagher
- Jiang-Hui Wang
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In Molecular Biology
- Guangping Gao
- Wei Zhan
- Thomas L. Gallagher
- Jiang-Hui Wang
- E. Murphy
- E. Aandahl
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- S. Offermanns
Citations in the corpus
- Doctoral Dissertation (2019, background): “triggers a much larger Ca release from the SR, this process has been coined the Ca induced Ca release (CICR).(53) In humans, approximately 30% of the increase in intracellular Ca is because of the influx through L‐type Ca channels.”
- Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury. (2008, background): “However, other groups have reported that PC and diazoxide enhance IF1 binding to the F 1 F 0 ATPase (4, 46, 47).”
- Calcium Signaling (2012, background): “For example, cardiac myocytes require a rapid (hundreds of milliseconds) wholecell calcium transient to trigger contraction every second (Bers 2002), whereas cells that are not electrically excitable typically display calcium oscillations that last for tens of seconds, and can have a periodicity of…”
- REVIEW ARTICLE Na + /Ca 2+ exchangers: three mammalian gene families control Ca 2+ transport (2007, background): “258, 3178–3182 68 Bers, D. M. (2002) Cardiac excitation–contraction coupling.”
- Mammalian G proteins and their cell type specific functions. (2005, background): “cAMP produced in response to Gs activation directly modulates the gating of hyperpolarization-activated, cyclic nucleotide-gated channels and activates protein kinase A (PKA) which in turn phosphorylates several proteins involved in excitation-contraction coupling including L-type Ca(2) channels, ph”
- Localized effects of cAMP mediated by distinct routes of protein kinase A. (2004, background): “The ubiquitous second messenger Ca(2) is essential in cardiac electrical activity and is the direct activator of the myofilaments, which cause contraction (27).”
- Role of the Autonomic Nervous System in Modulating Cardiac Arrhythmias (2014, background): “Sympathetic activation causes increasing calcium transient.(60) Vagal activation can reduce the atrial effective refractory period.”
- Adeno-associated virus as a delivery vector for gene therapy of human diseases (2024, methodology): “340,341 The CUPID trial evaluated overexpressing SERCA2a using rAAV1 (rAAV1.”