Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial.

By D. Andrews, C. Scott, P. Sperduto, A. Flanders, L. Gaspar, M. Schell, M. Werner-Wasik, W. Demas, J. Ryu, J. Bahary and 4 more. The Lancet, 2004

2,408 citations recorded by the source corpus.

Subfields: Genetics, Pulmonary and Respiratory Medicine, Surgery

View Paper: https://www.semanticscholar.org/paper/7510d8a1ce82391b2a0e6642bfc830c83b6e7f81

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Charles Swanton

In Pulmonary and Respiratory Medicine

1. Charles Swanton
2. Kenichi Sugihara

Citations in the corpus

• Volumetric modulated arc therapy: a review of current literature and clinical use in practice. (2011, background): “In the palliative setting, randomised data has shown improvements in survival with the combination of radiosurgery and whole brain radiotherapy (WBRT) compared with WBRT alone for brain metastases [134].”
• Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. (2010, background): “Most trials in brain metastasis include only a small proportion of RCC cases [61-63].”
• Stereotactic radiosurgery for brain metastases: analysis of outcome and risk of brain radionecrosis (2011, background): “Its efficacy when used alone or in combination with whole brain radiationtherapy (WBRT) has been demonstrated in several randomized trials and multi-institutional studies [1-8].”
• Stereotactic Radiosurgery Plus Whole-Brain Radiation Therapy vs Stereotactic Radiosurgery Alone for Treatment of Brain Metastases: A Randomized Controlled Trial (2007, background): “In more recent years, the importance of focal aggressive therapy combined with WBRT has been increasingly recognized.(3,4,22-24) Andrews et al(4) recently reported the results from RTOG 9508, a multi-institutional phase 3 trial of 333 patients with 1 to 3 brain metastases who received WBRT with or w”
• Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2019 for the treatment of colorectal cancer (2019, background): “When a prognosis of several years can be expected, whole‐brain radiother‐ apy in combination with stereotactic irradiation is con‐ sidered [140, 141].”
• Renal cell carcinoma (2017, background): “Most trials in brain metastasis include only a small proportion of RCC cases [61-63].”