Peptidotriazoles on solid phase: [1,2,3]-triazoles by regiospecific copper(i)-catalyzed 1,3-dipolar cycloadditions of terminal alkynes to azides.
By C. Tornøe, C. Christensen, M. Meldal. Journal of Organic Chemistry, 2002
7,324 citations recorded by the source corpus.
Subfields: Molecular Biology, Oncology, Organic Chemistry
View Paper: https://www.semanticscholar.org/paper/73176b04f1a50597ff4bfe9a57f9486b0b898336
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In Molecular Biology
In Organic Chemistry
Citations in the corpus
- Click Chemistry in Complex Mixtures: Bioorthogonal Bioconjugation (2014, background): “Copper-catalyzed azide-alkyne cycloaddition (CuAAC, Figure 4) (Rostovtsev et al., 2002; Tornøe et al., 2002; Worrell et al., 2013) has emerged as a highly versatile ligation process for bioconjugation applications of all types, except in living cells and tissues where free copper ions are toxic.”
- Photomediated controlled radical polymerization (2016, neutral): “The copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) was the first example of “click” chemistry.[290, 291] Since”