The evolution of sex-biased genes and sex-biased gene expression

By H. Ellegren, J. Parsch. Nature reviews genetics, 2007

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How researchers see this paper

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Toward discovery science of human brain function (2010, background): “Sexual dimorphism in human genomic expression (36) is known to affect numerous physiological variables that can influence the fMRI signal (37, 38).”
Genetics and Beyond – The Transcriptome of Human Monocytes and Disease Susceptibility (2010, background): “as environmental exposures [11,12], metabolic conditions [13], ageing [14,15] or gender [16–17].”
Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A Case for Sex-Specific Medicines (2010, background): “Viewed from another perspective, sexual dimorphism in gene expression occurs on a large scale and is widespread not only in mammals but across phyla (Rinn and Snyder, 2005; Ellegren and Parsch, 2007).”
Nothing in Genetics Makes Sense Except in Light of Genomic Conflict (2013, background): “Recent genome-wide gene expression studies indicate that the identity of gender-biased genes (with sex differences in expression) changes rapidly between closely related species (reviewed by Ellegren & Parsch 2007).”
Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “biased in expression, as might occur as a result of sex-specific selection, this can select for regulatory mechanisms that further limit expression levels in females or males (Ellegren and Parsch, 2007).”