Statistical tests for detection of misspecified relationships by use of genome-screen data.

By M. McPeek, Lei Sun. American Journal of Human Genetics, 2000

336 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/72859270d1d90be97349e27b1e279b852548f4cd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

Citations in the corpus

ml‐relate: a computer program for maximum likelihood estimation of relatedness and relationship (2006, neutral): “1998; Goodnight & Queller 1999; McPeek & Sun 2000).”
GRR: graphical representation of relationship errors (2001, background): “Statistics for verifying relationships through patterns of allele sharing have been proposed, with various degrees of sophistication, computing time requirements and assumptions (Boehnke and Cox, 1997; Goring and Ott, 1997; Broman and Weber, 1998; Epstein et al., 2000; McPeek and Sun, 2000).”
Detection and integration of genotyping errors in statistical genetics. (2002, background): “Similar issues apply to determining whether sibs are half sibs or full sibs in a genome scan (Thompson 1975, 1986; Lathrop et al. 1983; Boehnke and Cox 1997; Broman and Weber 1998; Ehm and Wagner 1998; Gordon et al. 1999a; Kumm et al. 1999; McPeak and Sun 2000; Sieberts et al. 2001).”
Population Structure and Cryptic Relatedness in Genetic Association Studies (2009, background): “McPeek and Sun (2000) showed how to augment the Markov model to describe the IBD process when the chromosomes correspond to an avuncular or first cousin pair.”
Common variants in MS4A4/MS4A6E, CD2uAP, CD33, and EPHA1 are associated with late-onset Alzheimer’s disease (2011, neutral): “Relationships among individuals in the family-based cohorts (MIRAGE and NIALOAD) were confirmed by pairwise genome-wide estimates of proportion identity-by-descent (IBD) using PREST softwar”