Generation of bispecific IgG antibodies by structure-based design of an orthogonal Fab interface

By Steven M. Lewis, Xiufeng Wu, A. Pustilnik, A. Sereno, F. Huang, Heather L Rick, Gurkan Guntas, Andrew Leaver-Fay, E. Smith, Carolyn Ho and 7 more. 2014

248 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology, Radiology, Nuclear Medicine and Imaging

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Andrew Leaver-Fay
2. Brian Kuhlman
3. David Baker
4. Tanja Kortemme
5. Jeffrey J. Gray
6. I. Samish
7. Jens Meiler
8. Ron Jacak

In Radiology, Nuclear Medicine and Imaging

1. Brian Kuhlman

Citations in the corpus

• Computationally Designed Bispecific Antibodies Using Negative State Repertoires (2016, methodology): “Nonetheless, several new strategies have been described in the past few years for generating IgG BsAbs either through post expression/purification biochemical methods (Labrijn et al., 2013; Spiess et al., 2013; Strop et al., 2012) or by the direct expression of correctly assembled IgG BsAbs (Bostrom”