Mitotic Abnormalities Induced by Silk Dyeing Industry Effluents in the Cells of Allium cepa

By R. Sudhakar, K. Gowda, G. Venu. 2001

285 citations recorded by the source corpus.

The silk dyeing industry effluents were examined for the induction of mitotic abnormalities in Allium cepa root system. Cytotoxicity of the effluent was studied by treating Allium cepa roots with different concentrations of effluent (25, 50, 75, 100%) for different durations (6, 12, 24, 48 h) along with control. The effluent inhibited cell division and a strong dosage effect was obvious from a decline in the mitotic index with the increase in effluent concentration and duration of treatment. The effluent also induced a wide range of mitotic abnormalities. The abnormalities observed included stickiness of chromosomes, fragments, bridges, laggards, binucleate cells and vacuolated nuclei. The results showed that silk dyeing industry effluents act as potential mutagens.

Subfields: Cell Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/721d551526abc242dafb3e3b17965fb1c39e308f

Citations in the corpus

• Allium Cepa Root Chromosomal Aberration Assay: A Review (2013, unknown): “Significant reduction in MI, noted in the present study may be due to the inhibition of DNA synthesis or the blocking in the G2 phase of the cell cycle [63].”
• Genotoxicity and mutagenicity of water contaminated with tannery effluents, as evaluated by the micronucleus test and comet assay using the fish Oreochromis niloticus and chromosome aberrations in onion root-tips (2006, unknown): “…soil pollutants have been demonstrated by several authors using the micronucleus assay in A. cepa and V. faba root tip cells (Grover and Kaur, 1999; Sudhakar et al., 2001; and Patra and Sharma, 2002), these authors having reported that the chromosomal changes most frequently observed were…”
• Allium cepa test in environmental monitoring: a review on its application. (2009, unknown): “abnormalities Meristematic cells Cytotoxicity and genotoxicity [44]”