Dynamics of global gene expression changes during mouse preimplantation development.

By T. Hamatani, M. G. Carter, A. Sharov, M. Ko. Developmental Cell, 2004

901 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Genetic programs in human and mouse early embryos revealed by single-cell RNA sequencing (2013, neutral): “Oocyte (3) Pronucleus (3) Zygote (2) 2-cell (3) 4-cell (4) 8-cell (11) Morula (3) Oocyte Pronucleus Zygote”
Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development (2011, result): “Similar data indicating expression of aurora C in early embryos, but not in later stages or most somatic tissues, can be obtained from published expression profiles (Hamatani et al., 2004) and public databases (see Fig.”
The maternal-to-zygotic transition: a play in two acts (2009, methodology): “…in situ hybridization analyses (Lecuyer et al., 2007) – have begun to uncover the scope of ZGA: up to 15% of the genome in D. melanogaster (Benoit et al., 2009; De Renzis et al., 2007; Lecuyer et al., 2007), over 12% in zebrafish (Mathavan et al., 2005) and over 15% in mice (Hamatani et al., 2004).”
mRNA-Seq whole-transcriptome analysis of a single cell (2009, result): “To get another independent line of support for our assay, we compared our mRNA-Seq assay with the NIH mouse 60-mer array data for four-cell stage embryo”
Roadmap to embryo implantation: clues from mouse models (2006, background): “Recently, global gene-expression profiles that were derived from microarray experiments have generated a comprehensive data set that covers nearly all mouse genes during preimplantation developmen”