Childhood maltreatment is associated with reduced volume in the hippocampal subfields CA3, dentate gyrus, and subiculum

By Martin H. Teicher, Carl M. Anderson, Ann Polcari. Proceedings of the National Academy of Sciences of the United States of America, 2012

670 citations recorded by the source corpus.

Subfields: Clinical Psychology, Developmental Neuroscience, Pediatrics, Perinatology and Child Health

View Paper: https://www.semanticscholar.org/paper/712ce3a557019ea5ce3d8343156c1cef0aa4d03a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Clinical Psychology

In Developmental Neuroscience

Martin Brüne

In Pediatrics, Perinatology and Child Health

Citations in the corpus

Automated Volumetry and Regional Thickness Analysis of Hippocampal Subfields and Medial Temporal Cortical Structures in Mild Cognitive Impairment (2014, methodology): “However, nearly all published applications of this technique have been to T1-weighted MRI with “routine” resolution on the order of 1 3 1 3 1 mm3 [e.g., Engvig et al., 2012; Hanseeuw et al., 2011; Iglesias et al., 2013; Lim et al., 2012; Pereira et al., 2013; Teicher et al., 2012].”
Childhood Adversity and Neural Development: Deprivation and Threat as Distinct Dimensions of Early Experience (2014, background): “Although early threat exposure has consistently been associated with reduced hippocampal volume in adults (Andersen and Teicher, 2008; Hart and Rubia, 2012; Teicher et al., 2012), studies of children have generally not found a relationship between threat exposure and hippocampal volume (De Bellis et”
Quantitative Comparison of 21 Protocols for Labeling Hippocampal Subfields and Parahippocampal Subregions in In Vivo MRI: Towards a Harmonized Segmentation Protocol (2015, background): “Recent advances in MRI technology have made it possible to visualize the hippocampal region with increasing detail, leading a growing number of researchers to attempt to label and quantify small substructures using in vivo MRI (Insausti et al., 1998; Small et al., 2000; Zeineh et al., 2001, 2003, 20”
More than a feeling: A unified view of stress measurement for population science (2018, background): “There is consistent evidence that early trauma exposure is associated with smaller hippocampal volume in adulthood (Teicher et al., 2012) and alterations in amygdala-dependent emotional processing, marked by increased threat sensitivity (McCrory et al.”
Annual Research Review: Enduring neurobiological effects of childhood abuse and neglect (2016, neutral): “In addition, any association between depression and hippocampal volume was lost once maltreatment was taken into account (Opel et al., 2014; Teicher et al., 2012).”
Behavior Problems After Early Life Stress: Contributions of the Hippocampus and Amygdala (2014, background): “In humans, one form of ELS, child maltreatment, is consistently related to smaller hippocampi in adults (30,43,44).”
A computational atlas of the hippocampal formation using ex vivo, ultra-high resolution MRI: Application to adaptive segmentation of in vivo MRI (2015, positive): “Nonetheless, both Yushkevich's method and ours have successfully been used to carry out subregion studies on large populations (Teicher et al., 2012; Das et al., 2012; Iglesias et al., 2013).”
Borderline Personality Disorder (2016, positive): “Abundant evidence suggests that childhood maltreatment is associated with reductions in volume of limbic areas and the corpus callosum, and that impulsivity in BPD is associated with alterations in blood flow in frontal cortical regions [71-74].”