Binding and condensation of plasmid DNA onto functionalized carbon nanotubes: toward the construction of nanotube-based gene delivery vectors.

By Ravi Singh, Davide Pantarotto, D. McCarthy, O. Chaloin, J. Hoebeke, C. Partidos, J. Briand, M. Prato, A. Bianco, Kostas Kostarelos. Journal of the American Chemical Society, 2005

720 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Materials Chemistry, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/6fb6f4da33b6c1a690e88bb5060b8b68c6316064

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Citations in the corpus

Carbon Nanotubes in Biology and Medicine: In vitro and in vivo Detection, Imaging and Drug Delivery (2009, methodology): “Although MWNTs exhibit less rich and attractive optical properties than SWNTs, their use in biological systems could be different from that of SWNTs due to their larger sizes, which could offer different platforms for different purposes, such as delivery of large biomolecules including DNA plasmids ”
Carbon nanotubes as nanomedicines: from toxicology to pharmacology. (2006, background): “Also from our laboratories, the work developed regarding the use of CNT as gene therapy vectors [2,33] and drug delivery systems [5,34] have shown that these engineered structures can effectively transport the genes and drugs inside mammalian cells.”
Biomedical applications of functionalised carbon nanotubes. (2005, background): “In 2004, our groups published the first studies (Pantarotto et al., 2004b; Singh et al., 2005) to demonstrate that CNT-mediated gene delivery and expression leading to production of marker proteins encoded in pDNA was possible.”