NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21

By J. Arron, M. Winslow, A. Polleri, C. Chang, Hai-Ping Wu, Xin Gao, J. Neilson, Lei Chen, Jeremy J. Heit, Seung K. Kim and 5 more. Nature, 2006

690 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/6f6abb4b17ef347a38d7ef46dd77d578d4d0b1fb

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Jennifer A. Doudna

In Molecular Biology

1. Jennifer A. Doudna
2. Steven Lin
3. Feng Zhang
4. Lei S. Qi
5. P. Hsu
6. Haifeng Wang
7. Marie La Russa
8. Rodolphe Barrangou

In Public Health, Environmental and Occupational Health

1. Jennifer A. Doudna

Citations in the corpus

• Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery (2014, methodology): “To test these effects at other genomic loci, we programmed Cas9 RNPs to target the DYRK1 gene, which is important for brain development, autism and Downs Syndrome (Arron et al., 2006; Fotaki et al., 2002; O'Roak et al., 2012).”