DNA methylation profiling in the clinic: applications and challenges

By Holger Heyn, Manel Esteller. Nature reviews genetics, 2012

732 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/6f5ca0cd6d3305771c9399830ae8add252cba86d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Peter A. Jones
2. G. Liang
3. F. Lay
4. S. Baylin

In Molecular Biology

1. Peter A. Jones
2. G. Liang
3. Daniel D. De Carvalho
4. F. Lay
5. Xiaojing Yang
6. Han F Han
7. S. Baylin
8. Manel Esteller

Citations in the corpus

• Next-Generation Sequencing Technology: Current Trends and Advancements (2023, background): “The knowledge and data generated through whole-genomewide sequencing in humans, plants, and animals [64] have helped scientists to gain better insights into these epigenetic alterations, especially DNA methylation and hydroxymethylation.”
• Gene Body Methylation can alter Gene Expression and is a Therapeutic Target in Cancer (2014, background): “Much effort has been invested to determine the molecular mechanisms underlining the clinical efficacies of 5-Aza-CR and 5-Aza-CdR (Heyn and Esteller, 2012; Kelly et al., 2010a).”