Human genetics: You must remember this...

By M. Skipper. Nature reviews genetics, 2003

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Forebrain gene expression domains and the evolving prosomeric model. (2003, background): “The rostral hypothalamus correlates topographically with early expression of Six3, which extends from the septum to neurohypophysis [46]; this was the best evidence so far for defining molecularly the old p6 prosomere; however, analysis of the Six3 or Hesx1 knockout mice [ 47 ,48] revealed a loss of”
Eya protein phosphatase activity regulates Six1–Dach–Eya transcriptional effects in mammalian organogenesis (2003, background): “, and it is essential for eye and other rostral structure development in mice by means of direct repression of Wnt gene”
Signalling in neural development: WNTS in the vertebrate nervous system: from patterning to neuronal connectivity (2005, background): “fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=20473">SIX3 is expressed in the most anterior part of the neural plate, and functions as a repressor of WNT1 in anterior region”