Developmental cell biology: Eph receptor signalling casts a wide net on cell behaviour
By E. Pasquale. Nature reviews. Molecular cell biology, 2005
1,060 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/6e0436495582fcb4fafba53bb4796ab45acf475a
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In Cellular and Molecular Neuroscience
In Developmental Neuroscience
In Molecular Biology
Citations in the corpus
- Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit. (2014, background): “Ephrin/Eph family members are recognized as local mediators of cell function through contact-dependent processes in many tissues in development and in maturity.(88,89) A particular feature is their capacity for bi-directional signaling, in that when an ephrin acts upon its corresponding Eph receptor”
- Eph-ephrin bidirectional signaling in physiology and disease. (2008, background): “Because Eph receptors/ ephrins are expressed in various other types of stem cells, they are also likely to be present in cancer stem cells (Pasquale, 2005).”
- Brain micro-ecologies: neural stem cell niches in the adult mammalian brain (2008, background): “Eph/ephrins are another large class of membraneassociated receptors and ligands with diverse roles during development, including axon guidance, cell migration and synaptogenesis (reviewed in Pasquale 2005).”
- Ephrins and Eph receptors in stem cells and cancer. (2010, background): “The interaction of Eph receptors with ephrins can result in bidirectional signaling, where signals are conveyed not only into the receptor expressing cell (forward signaling) but also into the ligand expressing cell (reverse signaling) [6,7].”
- Molecular mechanisms of axon guidance. (2006, background): “The EphA and EphB proteins are receptor tyrosine kinases, named based on their preferential binding to the EphrinA and EphrinB family respectively (Pasquale, 2005).”
- Bidirectional ephrinB2-EphB4 signaling controls bone homeostasis. (2006, background): “…molecules ephrinB (B1wB3) are preferential ligands for the tyrosine kinase receptors EphB (B1wB6), while ephrinA proteins (A1wA5) function as ligands for EphA (A1wA10) receptors (Himanen and Nikolov, 2003; Kullander and Klein, 2002; Murai and Pasquale, 2003; Palmer and Klein, 2003; Pasquale, 2005).”