The eukaryotic linear motif resource ELM: 10 years and counting
By Holger Dinkel, K. Roey, S. Michael, Norman E. Davey, Robert J. Weatheritt, D. Born, Tobias Speck, Daniel Krüger, G. Grebnev, Marta Kuban and 10 more. Nucleic Acids Res., 2013
314 citations recorded by the source corpus.
The eukaryotic linear motif (ELM http://elm.eu.org) resource is a hub for collecting, classifying and curating information about short linear motifs (SLiMs). For >10 years, this resource has provided the scientific community with a freely accessible guide to the biology and function of linear motifs. The current version of ELM contains ∼200 different motif classes with over 2400 experimentally validated instances manually curated from >2000 scientific publications. Furthermore, detailed information about motif-mediated interactions has been annotated and made available in standard exchange formats. Where appropriate, links are provided to resources such as switches.elm.eu.org and KEGG pathways.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/6d9e50cd7415aa23dd3ef4c4c12fbd53da08da64
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Citations in the corpus
- High-throughput prediction of RNA, DNA and protein binding regions mediated by intrinsic disorder (2015, methodology): “In particular, IDPs and IDRs were shown to be important for the protein–protein interactions (PPIs) and are enriched in the RNA- and DNA-binding proteins (1,11–16).”
- A highly conserved program of neuronal microexons is misregulated in autistic brains (2014, methodology): “Globular domains known to bind linear motifs and lipids were extracted from the ELM database (Dinkel et al., 2014) and Pfam (Finn et al.”
- ELM 2016—data update and new functionality of the eukaryotic linear motif resource (2015, methodology): “49 novel1 ELM classes that have been added since the last ELM publication (21), together with the number of associated instances (middle”