The central autonomic nervous system: conscious visceral perception and autonomic pattern generation.

By Clifford B. Saper. Annual Review of Neuroscience, 2002

794 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/6d2a4feb76db39370529a042c9010de8473692ae

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Neural mechanisms of autonomic, affective, and cognitive integration (2005, background): “Patterns of autonomic response within and across sympathetic, parasympathetic and humoral axes are differentially generated in different behavioral contexts (Ekman et al., 1983; Porges, 1985; Morrison, 2001; Saper, 2002).”
Anterior Insular Cortex and Emotional Awareness (2013, positive): “In rats, the insular cortex is interconnected with the autonomic system as well as limbic and frontal regions (Saper and Loewy, 1980; Saper, 1982; Allen et al., 1991) and has been shown to contain a viscerotopic map (Cechetto and Saper, 1987).”
Histamine in the nervous system. (2008, background): “Histamine neurons in the TMN are part of the central representations of the sympathicus (102, 371, 635) and control sympathoadrenal outflow through H3R (102).”
The sympathetic control of blood pressure (2006, neutral): “baroreflex is also under humoral control (3).”
The Endocannabinoid System as an Emerging Target of Pharmacotherapy (2006, background): “Additionally, cannabinoids can increase the intake of palatable foods by acting at sites in the brainstem (Miller et al., 2004), which also have reciprocal neural connections with forebrain limbic structures (Saper, 2002).”
Emotion and the Prefrontal Cortex: An Integrative Review (2017, background): “fleeing) to cope with immediate challenges in the environment (Bandler et al., 2000; Critchley & Harrison, 2013; Saper, 2002; Ulrich-Lai & Herman, 2009).”
Brain mediators of cardiovascular responses to social threat, Part I: Reciprocal dorsal and ventral sub-regions of the medial prefrontal cortex and heart-rate reactivity (2009, background): “A wealth of non-human animal literature supports a connection between MPFC and autonomic control of the heart (Bandler et al., 2000; Barbas et al., 2003; Devinsky et al., 1995; Saper, 2002), and MPFC has been referred to as “visceromotor cortex,” in contrast to lateral orbital “viscerosensory” areas”
A meta-analysis of heart rate variability and neuroimaging studies: implications for heart rate variability as a marker of stress and health. (2012, background): “, 2009c), and a variety of other peripheral responses to stressors (Lane and Wager, 2009) through connectivity with the brainstem (Keay and Bandler, 2001; Saper, 2002; Wager et al., 2008a, 2009b).”
Corticostriatal-hypothalamic circuitry and food motivation: integration of energy, action and reward. (2005, neutral): “[21,22]).”
The Salience Network: A Neural System for Perceiving and Responding to Homeostatic Demands (2019, background): “These ideas represented a synthesis of many related prior notions put forth by thought leaders in the field (Mesulam and Mufson, 1982b; Craig, 2002, 2003; Saper, 2002; Critchley, 2005; Heimer and Van Hoesen, 2006).”
The Autonomic Brain: An Activation Likelihood Estimation Meta-Analysis for Central Processing of Autonomic Function (2013, background): “Nevertheless, a central autonomic network (CAN) has been proposed based on observations from animal experiments using electrical stimulation and from tracer studies (Cechetto and Saper, 1990; Benarroch, 1993; Verberne and Owens, 1998; Saper, 2002).”
Whole-brain mapping of direct inputs to midbrain dopamine neurons. (2012, positive): “The central autonomic system receives taste and visceral information and regulates various autonomic responses (Saper, 2002; Yamamoto, 2006).”
An evaluation of current perspectives on consciousness and pain in fishes (2004, background): “The creation of a subjective feeling of pain is arguably a complex affair, including spinal, brainstem, thalamic and cerebral structures, as well as essential autonomic nervous system feedback (Willis and Westlund 1997; Chapman and Nakamura 1999; Saper 2002).”
The somatic marker hypothesis: a critical evaluation. (2006, background): “For a more detailed account of regions of the brain that represent and regulate the periphery, see Craig (2002), Saper (2002), Critchley (2002, 2004), and Bernston et al. (2003).”
Regulation of anterior insular cortex activity using real-time fMRI (2007, result): “The experiments conducted so far (Penfield and Faulk, 1955; Oppenheimer et al., 1992; Sander and Klingelhöfer, 1995; Saper, 2002) indicate that the human insular cortex does contain autonomic control sites, however these results were obtained from patients and using poor anatomical localization.”
Visceral influences on brain and behavior. (2013, positive): “The notion that viscerosensory insula cortex supports more general emotional experiences is further highlighted by functional neuroanatomists (Craig, 2002; Saper, 2002).”
Migraine pathophysiology: anatomy of the trigeminovascular pathway and associated neurological symptoms, CSD, sensitization and modulation of pain (2013, background): “The hypothalamus plays a critical role in autonomic and endocrine regulation [112], and has been implicated in the premonitory symptoms frequently experienced by migraineurs such as sleep–wake cycle disturbances, changes in mood, appetite, thirst, and urination [40].”