Dominance of IL-12 Over IL-4 in γδ T Cell Differentiation Leads to Default Production of IFN-γ: Failure to Down-Regulate IL-12 Receptor β2-Chain Expression1

By Z. Yin, Dong-hong Zhang, T. Welte, G. Bahtiyar, Sungsoo Jung, Lanzhen Liu, Xin-Yuan Fu, A. Ray, J. Craft. Journal of Immunology, 2000

88 citations recorded by the source corpus.

Subfields: Immunology, Oncology

View Paper: https://www.semanticscholar.org/paper/6b4481011a1b42ad08ee40ac72ee75c5c1573f6f

How researchers see this paper

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In Immunology

1. Laurie H. Glimcher
2. R. O’Brien
3. W. Born

In Oncology

1. Laurie H. Glimcher

Citations in the corpus

• γδ T‐cell receptors: functional correlations (2007, background): “In vitro studies suggest that the functional state of a gd T cell cannot be easily altered (76).”
• T-Bet Expression and Failure of GATA-3 Cross-Regulation Lead to Default Production of IFN-γ by γδ T Cells1 (2002, methodology): “We and others have previously demonstrated that murine T cells predominantly produce IFN- upon activation (11, 16).”