Controlling TGF-β signaling

By J. Massagué, Ye-Guang Chen. Genes & Development, 2000

1,767 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/6b37892443c32a9fee4396d316c95fc224490cf4

How researchers see this paper

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In Molecular Biology

1. J. Massagué
2. J. Seoane
3. K. Helin
4. D. Wotton
5. A. Bracken
6. C. Hill
7. P. Ingham
8. Oliver Eickelberg

Citations in the corpus

• TGFβ in Cancer (2008, background): “A structurally diverse group of proteins (ligand traps) that “trap” TGFβ family members to limit their access to membrane receptors play critical roles during morphogenesis of the embryo and in the adult (De Robertis and Kuroda, 2004; Massagué and Chen, 2000).”
• Genetic Analysis of the Mammalian Transforming Growth Factor-β Superfamily (2002, background): “These Smad proteins contain a characteristic C-terminal MH2 domain, but their N terminus has little similarity with typical MH1 domains (49).”
• Hedgehog signaling in animal development: paradigms and principles. (2001, background): “…fall into a few large families of secreted peptide factors: theWnt (Wodarz and Nusse 1998), fibroblast growth factor (Szebenyi and Fallon 1999), TGF- superfamily (Massague and Chen 2000), plateletderived growth factor (Betsholtz et al. 2001), ephrin (Bruckner and Klein 1998), and Hedgehog families.”
• Smad transcription factors. (2005, methodology): “1; for reviews, see Massagué and Chen 2000; Shi and Massagué 2003).”
• Androgen receptor in prostate cancer. (2004, background): “The prostate cancer cell line TSU-Pr1 has alternately been reported to proliferate (251) or be growth inhibited (252) in response to TGF treatment.”
• Cloning of Transforming Growth Factor-β1 (TGF-β1) and Its Type II Receptor from Zebrafish Ovary and Role of TGF-β1 in Oocyte Maturation (2003, background): “factors, coactivators, or corepressors (25, 26).”
• Cellular and molecular pathobiology of pulmonary arterial hypertension. (2004, background): “TGF- superfamily. The TGF- superfamily is composed of multifunctional mediators, including the TGFisoforms (TGF-1–3), the bone morphogenetic proteins (BMPs), activins, and growth and differentiation factors ( 33 ,34).”