Evidence of a dissociation pattern in resting-state default mode network connectivity in first-episode, treatment-naive major depression patients.

By Xueling Zhu, Xiang Wang, Jin Xiao, J. Liao, Shuqiao Yao. Biological Psychiatry, 2012

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How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Depressive Rumination, the Default-Mode Network, and the Dark Matter of Clinical Neuroscience (2015, methodology): “Importantly, Bermann et al. (32) and Zhu and colleagues (35) reported that stronger connectivity between sgPFC and the DMN predicted higher levels of ruminative responding in MDD.”
The cingulum bundle: Anatomy, function, and dysfunction (2018, neutral): “, 2010), ADHD (Konrad and Eickhoff, 2010), depression (Öngür et al., 2010; Zhu et al., 2012), PTSD (Bluhm et al.”
The role of the posterior cingulate cortex in cognition and disease. (2014, background): “Recently a number of MRI studies have shown abnormal PCC functional connectivity in major depression, although the abnormalities reported are variable (Bluhm et al., 2009; Zhou et al., 2010; Berman et al., 2011; Zhu et al., 2012).”
Reduced default mode network functional connectivity in patients with recurrent major depressive disorder (2019, neutral): “The first study focusing on the DMN in MDD reported increased DMN FC (7), although similar studies found both increased and decreased DMN FC in MDD (8, 9).”