A step-up approach or open necrosectomy for necrotizing pancreatitis.

By H. V. van Santvoort, M. Besselink, O. Bakker, H. S. Hofker, M. Boermeester, Cornelis H. C. Dejong, H. van Goor, A. Schaapherder, C. V. van Eijck, T. Bollen and 18 more. New England Journal of Medicine, 2010

1,504 citations recorded by the source corpus.

Subfields: Rheumatology, Surgery

View Paper: https://www.semanticscholar.org/paper/6ac0728172563e5287058624dad35210102daeb2

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In Surgery

1. Harry van Goor
2. Jean-Louis Vincent
3. R. Moreno

Citations in the corpus

• Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012 (2013, background): “invasive, step-up approach was better tolerated by patients and had a lower mortality than open necrosectomy in necrotizing pancreatitis [112], although areas of uncertainty exist, such as definitive documentation of infection and appropriate length of delay.”
• IAP/APA evidence-based guidelines for the management of acute pancreatitis. (2013, methodology): “Remarks: a multicenter RCT in 88 patients with (suspected) infected necrotizing pancreatitis showed that a step-up approach of percutaneous (retroperitoneal) catheter drainage, followed, if needed, by minimally invasive necrosectomy decreased major short-term complications such as new onset multi-or”