Selective killing of ATM- or p53-deficient cancer cells through inhibition of ATR.

By P. Reaper, M. Griffiths, Joanna M. Long, J. Charrier, Somhairle Maccormick, P. Charlton, J. Golec, Jack Pollard. Nature Chemical Biology, 2011

614 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/6a4af35a6f1be760fc32ec144d8e506c58265148

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In Molecular Biology

1. L. Zou
2. Alexandre Maréchal

In Oncology

1. L. Zou
2. Alexandre Maréchal

Citations in the corpus

• DNA damage sensing by the ATM and ATR kinases. (2013, background): “More recently, ATR-specific inhibitors have also become available and were shown to enhance the sensitivity of cancer cells to cisplatin and irradiation (Charrier et al. 2011; Reaper et al. 2011; Pires et al. 2012).”