Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen

By Justin J. Taylor, R. Martinez, P. Titcombe, Laura O Barsness, Stephanie R. Thomas, N. Zhang, Shoshana D. Katzman, M. Jenkins, D. Mueller. 2012

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Both deletion and anergy shape B cell tolerance to membrane-bound antigens.

Subfields: Immunology, Radiology, Nuclear Medicine and Imaging

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Citations in the corpus

• Somatically hypermutated Plasmodium-specific IgM+ memory B cells are rapid, plastic, early responders upon malaria rechallenge (2016, methodology): “In all experiments, splenocytes were first stained with a decoy reagent and then with the MSP1 PE tetramer to exclude cells binding other components of the tetramer (Taylor et al., 2012a).”