The BIG Data Center: from deposition to integration to translation

By Wenming Zhao, Jingfa Xiao. Nucleic Acids Res., 2016

444 citations recorded by the source corpus.

Biological data are generated at unprecedentedly exponential rates, posing considerable challenges in big data deposition, integration and translation. The BIG Data Center, established at Beijing Institute of Genomics (BIG), Chinese Academy of Sciences, provides a suite of database resources, including (i) Genome Sequence Archive, a data repository specialized for archiving raw sequence reads, (ii) Gene Expression Nebulas, a data portal of gene expression profiles based entirely on RNA-Seq data, (iii) Genome Variation Map, a comprehensive collection of genome variations for featured species, (iv) Genome Warehouse, a centralized resource housing genome-scale data with particular focus on economically important animals and plants, (v) Methylation Bank, an integrated database of whole-genome single-base resolution methylomes and (vi) Science Wikis, a central access point for biological wikis developed for community annotations. The BIG Data Center is dedicated to constructing and maintaining biological databases through big data integration and value-added curation, conducting basic research to translate big data into big knowledge and providing freely open access to a variety of data resources in support of worldwide research activities in both academia and industry. All of these resources are publicly available and can be found at http://bigd.big.ac.cn.

Subfields: Genetics, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/69732dcf45024f28e5c43de68d1208f6e737eada

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Yīmíng Bào
2. Andrew E. Teschendorff
3. Zhang Zhang

In Molecular Biology

1. Zhen Yang
2. Haonan Yuan
3. Tao Jiang
4. Yīmíng Bào
5. Wanying Wu
6. Andrew E. Teschendorff
7. Runsheng Chen
8. J. Qu

Citations in the corpus

• Database Resources of the National Genomics Data Center, China National Center for Bioinformation in 2022 (2021, background): “Therefore, CNCB-NGDC is devoted to empowering accelerated progresses in life and health sciences by providing open access to a suite of database resources through big data archive, curation, integration and analysis (1–5).”