Depression Is the Leading Cause of Disability Around the World.

By M. Friedrich. Journal of the American Medical Association (JAMA), 2017

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Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial. (2021, background): “Major depressive disorder is the leading cause of disability worldwide (1, 2), and approximately 50% of patients meet criteria for treatment-resistant depression (3).”
Detection of Depression-Related Posts in Reddit Social Media Forum (2019, background): “In many countries depression is still under-diagnosed and left without any adequate treatment which can lead into a serious self-perception and at its worst, to suicide [2].”
Anxiety and depression in Canada during the COVID-19 pandemic: A national survey. (2020, background): “Keywords: COVID-19, depression, anxiety, substance use, mental health access Mood and anxiety disorders are the most prevalent mental health problems in Canada (McRae, O’Donnell, Loukine, Rancourt, & Pelletier, 2016) and throughout the world (Friedrich, 2017; Liua et al., 2019).”