Qscore: An algorithm for evaluating SEQUEST database search results

By Roger E. Moore, M. K. Young, Terry D. Lee. Journal of the American Society for Mass Spectrometry, 2002

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The beginning of a beautiful friendship: cross-linking/mass spectrometry and modelling of proteins and multi-protein complexes (2010, methodology): “, 2007), and using the target-decoy approach, combining the ordinary (target) database usually with an inverted (decoy) database (Moore et al., 2002; Kislinger et al., 2003; Peng et al., 2003; Sennels et al., 2009).”
Target-Decoy Search Strategy for Mass Spectrometry-Based Proteomics (2010, methodology): “Proteins— Protein reversal is by far the simplest and most widely used method for creating decoy sequences (see Note 2 for a simple Perl script to create a concatenated target-decoy sequence list based on an input target sequence list) (17,18).”
mProphet: automated data processing and statistical validation for large-scale SRM experiments (2011, methodology): “The principle of decoy transitions is conceptually related to the decoy database approach used for the database searches of shotgun proteomics dat”
Protein Identification False Discovery Rates for Very Large Proteomics Data Sets Generated by Tandem Mass Spectrometry* (2009, methodology): “Various approaches have been developed to estimate the reliability of PSMs (Keller, Nesvizhskii et al. 2002; Moore, Young et al. 2002; Elias and Gygi 2007; Kall, Storey et al. 2008).”