Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells

By M. Giarratana, L. Kobari, H. Lapillonne, D. Chalmers, L. Kiger, T. Cynober, M. Marden, H. Wajcman, L. Douay. Nature Biotechnology, 2005

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Chromatin signatures in multipotent human hematopoietic stem cells indicate the fate of bivalent genes during differentiation (2009, background): “The best characterized pathways for in vitro differentiation of the CD34 or CD133 cells are the production of erythrocyte precursor cells, which can be further induced to mature red blood cells (Giarratana et al., 2005).”