AlphaFold2 can predict structural and phenotypic effects of single mutations

By J. Mcbride, Konstantin Polev, Vladimir Reinharz, B. Grzybowski, Tsvi Tlusty. 2022

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Yi Zhao
2. Runsheng Chen
3. Zhenyu Yang
4. Xiaoxi Zeng

Citations in the corpus

• AlphaFold2 and its applications in the fields of biology and medicine (2023, background): “Although there are researches showing that AF2 could predict the phenotypic effect of missense mutations, 209,210 it was also observed that the performance of missense mutations prediction is not good in other studies, 211 and there were only weak or no correlations between the output metrics of…”