Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors

By E. Kirson, V. Dbalý, F. Tovaryš, J. Vymazal, J. Soustiel, A. Itzhaki, D. Mordechovich, Shirley Steinberg-Shapira, Zoya Gurvich, R. Schneiderman and 6 more. Proceedings of the National Academy of Sciences of the United States of America, 2007

841 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Biophysics

View Paper: https://www.semanticscholar.org/paper/671e40953bbf240cb1e4e0b54c04d7796971ebef

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

1. Michael A. Nitsche
2. Ulf Ziemann
3. Walter Paulus
4. Simone Rossi
5. Agnes Flöel

Citations in the corpus

• Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma: A Randomized Clinical Trial. (2015, background): “Duration of treatment with TTFields, median (range), mo 9 (1-58) 9 (1-58)”
• Evidence-based guidelines on the therapeutic use of transcranial direct current stimulation (tDCS). (2017, background): “In fact, continuous tACS at 200 kHz could selectively destroy dividing cells by targeting the inhomogeneous fields present at the bridge separating the daughter cells that interfere with spindle tubulin orientation and induce dielectrophoresis (Kirson et al., 2007).”
• Effect of Tumor-Treating Fields Plus Maintenance Temozolomide vs Maintenance Temozolomide Alone on Survival in Patients With Glioblastoma: A Randomized Clinical Trial (2017, neutral): “0 (70-100) 90-100 308 (66) 149 (65) ≤80 154 (33) 74 (32) Missing 4 (1) 6 (3) Sex Men 316 (68) 157 (69) Women 150 (32) 72 (31) Region United States 221 (47) 118 (52) Outside the United States 245 (53) 111 (48) Race/ethnicity White 416 (89) 201 (88) African American 3 (1) 1 (<1) Asian 27 (6) 19 (8) Hi”