Photodynamic therapy: a new antimicrobial approach to infectious disease?

By Michael R Hamblin, T. Hasan. Photochemical and Photobiological Sciences, 2004

1,941 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Ophthalmology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/6702ebd5a801bd41f8eeb798c4cab1117f5f89ba

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

1. K. Konopka
2. T. Gośliński
3. Michael R Hamblin
4. M. Karimi

In Ophthalmology

1. K. Konopka
2. T. Gośliński

In Pulmonary and Respiratory Medicine

1. K. Konopka
2. T. Gośliński
3. Michael R Hamblin

Citations in the corpus

• Photodynamic Therapy in Dentistry (2007, methodology): “A few studies have evaluated the use of PACT in animal models or in clinical trials, mainly for viral lesions, acne, gastric infection by Helicobacter pylori, and brain abscesses (reviewed by Hamblin and Hasan, 2004; O'Riordan et al., 2005).”
• Photodynamic therapy in the treatment of microbial infections: Basic principles and perspective applications (2006, background): “A further increase in the overall photoefficiency is induced by the replacement of one N-methyl group in tetrameso(N-alkyl-pyridyl)-substituted porphyrins by longer hydrocarbon chains, which should result in a progressive increase in the hydrophobicity [45,51,52].”
• Antimicrobial strategies centered around reactive oxygen species--bactericidal antibiotics, photodynamic therapy, and beyond. (2013, background): “PDT has mostly been developed as a cancer therapy (Agostinis et al., 2011), but recently has been proposed as an antimicrobial therapy (Hamblin & Hasan, 2004).”
• Photodynamic therapy for localized infections – state of the art (2009, neutral): “Throughout the years since those times there have been additional reports of bacteria being killed or inactivated by various combinations of PS and light (9).”
• Methylene blue in photodynamic therapy: From basic mechanisms to clinical applications. (2005, background): “Hamblin and Hasan [ 111 ] reviewed recently the area of photoinactivation of microorganisms by PDT emphasizing the double selectivity (light and drug localization) and the fact that it works in multi-resistant strains and does not induce resistance.”
• Photophysics and photochemistry of photodynamic therapy: fundamental aspects (2009, background): “PDT has achieved significant inactivation of gram-positive and gram-negative bacteria and is a promising tool to overcome the problem of (multi-) drug resistance of bacteria and to treat viral, fungal and parasitic infections (antimicrobial PDT has been reviewed in [5, 6]).”