Zebrafish: a model system for the study of human disease.

By Kimberly A. Dooley, Leonard I. Zon. Current Opinion in Genetics and Development, 2000

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The behaviour and ecology of the zebrafish, Danio rerio (2007, background): “The zebrafish is increasingly important in biomedical research (Dooley & Zon, 2000; Shin & Fishman, 2002), particularly as a model of human disease (Berghmans et al., 2005; Guyon et al., 2006) and for the screening of therapeutic drugs (Rubinstein, 2003, 2006).”
Zebrafish as a model vertebrate for investigating chemical toxicity. (2005, background): “…to identify genes affected by the exposure to various toxicants, mutant models are useful for studying human diseases (Amatruda et al., 2002; Barut and Zon, 2000; Dodd et al., 2000; Dooley and Zon, 2000; Knapik, 2000; Ward and Lieschke, 2002; van Heyningen, 1997; Vascotto et al., 1997; Zon, 1999).”
Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish (2009, background): “In addition to larvae studies, behavioral phenotyping of adult zebrafish also represents an important direction of research [14] [15] [16] [17].”
Medaka — a model organism from the far east (2002, background): “Notably, the zebrafish screens have yielded some mutants with diseases that closely resemble human genetic diseases, and therefore can serve as models for the”