Soft biological materials and their impact on cell function.

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How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Cell mechanics: integrating cell responses to mechanical stimuli. (2007, background): “1 kPa to an approximate upper limit of near 40 kPa (8) for myocytes, similar to the range of stiffness measured for many soft tissues (9).”
Mechanotransduction in development: a growing role for contractility (2009, background): “, which range from 17 Pa (human fat) to 310 MPa (the rat Achilles tendon”
Mechanics, malignancy, and metastasis: The force journey of a tumor cell (2009, neutral): “5 kPa), skeletal muscle (50 kPa), cartilage (950 kPa) [54].”
Fluid–structure interaction involving large deformations: 3D simulations and applications to biological systems (2014, background): “100 Pa for the brain to 100000 Pa for soft cartilage [33].”
Fibroblast adaptation and stiffness matching to soft elastic substrates. (2007, methodology): “10,000 Pa for muscle, and even greater stiffnesses for cartilage and bone (1).”