Navigating the chaperone network: an integrative map of physical and genetic interactions mediated by the hsp90 chaperone.
By Rongmin Zhao, Michael Davey, Y. Hsu, P. Kaplanek, A. Tong, A. Parsons, Nevan J. Krogan, G. Cagney, D. Mai, Jack Greenblatt and 3 more. Cell, 2005
855 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/65fb74a9863b9730a75b85a8afeb2e5a70a31f09
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In Molecular Biology
- Ryuji Hamamoto
- Yusuke Nakamura
- Makoto Nakakido
- Trey Ideker
- Nevan J. Krogan
- G. Toyokawa
- K. Ueda
- L. Whitesell
Citations in the corpus
- HSP90 and the chaperoning of cancer (2005, methodology): “These were detected by screening a library of 4,700 viable-yeast gene mutants for hypersensitivity to GELDANAMYCIN , a small-molecule inhibitor of HSP90 functio”
- Differential network biology (2012, background): “For example, static genetic networks have been very effective at identifying novel interactions underlying DNA replication (Collins et al , 2007; Nagai et al , 2008; Lambert et al , 2010), RNA splicing (Wilmes et al , 2008) and protein folding (Zhao et al , 2005).”
- SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation. (2014, background): “293T cells were co-transfected with a FLAGSMYD2 expression vector and four different lengths of HA-HSP90AB1 vectors ([1–724], [1–500], [250–724] and [500–724]).”
- Toward a Comprehensive Atlas of the Physical Interactome of Saccharomyces cerevisiae*S (2007, background): “Similarly Swc4 and Yaf9 are shared components of SWR-C and NuA4, whereas the actin-related proteins Act1 and Arp4 are part of SWR-C, NuA4, and INO80, but not the Tah1-Pih1, complexes.”
- The Response to Heat Shock and Oxidative Stress in Saccharomyces cerevisiae (2012, background): “…only a small number of yeast Hsp90 clients have been experimentally verified, genomic and proteomic approaches are being used to identify novel clients with the Heat and Oxidant Resistance 1165 goal of trying to establish the complete substrate complement in a single organism (Zhao et al. 2005b).”