Connecting copper and cancer: from transition metal signalling to metalloplasia
By Eva J. Ge, Ashley I. Bush, A. Casini, P. Cobine, J. Cross, G. DeNicola, Q. Dou, K. Franz, Vishal M. Gohil, Sanjeev Gupta and 14 more. Nature Reviews. Cancer, 2021
1,073 citations recorded by the source corpus.
Subfields: Nutrition and Dietetics, Oncology, Pulmonary and Respiratory Medicine
View Paper: https://www.semanticscholar.org/paper/65bdf3cc7970665007731519a3b59154e8092795
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In Nutrition and Dietetics
In Oncology
In Pulmonary and Respiratory Medicine
Citations in the corpus
- Copper metabolism in cell death and autophagy (2023, background): “In addition, high serum copper levels have been observed in various cancers in humans and may increase the risk of breast, lung, liver, colorectal, prostate, oral, or thyroid cancers [19].”
- Targeting cell death pathways for cancer therapy: recent developments in necroptosis, pyroptosis, ferroptosis, and cuproptosis research (2022, background): “Cu is a crucial component for various physiological processes, especially tumor growth and metastasis, which have a heightened requirement for Cu [72].”
- Copper induces cell death by targeting lipoylated TCA cycle proteins (2022, background): “Copper is a double-edged sword – it is essential as a co-factor for enzymes across the animal kingdom, and yet even modest intracellular concentrations can be toxic, resulting in cell death (2).”