Cancer stem cell definitions and terminology: the devil is in the details
By P. Valent, D. Bonnet, R. Maria, T. Lapidot, M. Copland, J. Melo, C. Chomienne, F. Ishikawa, J. Schuringa, G. Stassi and 12 more. Nature Reviews. Cancer, 2012
694 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/65af9fd77c75e1c9ea3ff65807b0314c27301280
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In Molecular Biology
Citations in the corpus
- CD44v6 is a marker of constitutive and reprogrammed cancer stem cells driving colon cancer metastasis. (2014, background): “their cell-surface-marker expression, are the unique source of all tumor cells and responsible for tumor propagation and relapse (Valent et al., 2012).”
- Spherical Cancer Models in Tumor Biology (2015, background): “…of tumorospheres; indeed, contrary to the use of other sphere models, that of the tumorosphere does not seek to mimic cancer tissues but rather to study CSC properties (Table 3): it is admitted that tumorospheres do not fully replicate the 3D structure and environment of an in vivo tumor [108].”
- Cancer Stem Cells (CSCs) in Drug Resistance and their Therapeutic Implications in Cancer Treatment (2018, background): “Cancer stem cells (CSCs), also known as tumor-initiating cells (TICs), have been intensively studied in the past decade, focusing on the possible source, origin, cellular markers, mechanism study, and development of therapeutic strategy targeting their pathway [23, 24].”