Human Neuroblasts Migrate to the Olfactory Bulb via a Lateral Ventricular Extension

By M. Curtis, Monica Kam, U. Nannmark, Michelle F. Anderson, Mathilda Zetterström Axell, C. Wikkelsø, S. Holtås, W. V. van Roon-Mom, T. Björk-Eriksson, C. Nordborg and 4 more. 2007

902 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Neurology

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Citations in the corpus

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions (2011, background): “Because of limitations of tools that can be applied to humans, there is still ongoing debate about the existence of adult SVZ neurogenesis and a prominent RMS of new neurons in humans (Curtis et al., 2007; Sanai et al., 2004; Wang et al., 2011).”
The Glial Nature of Embryonic and Adult Neural Stem Cells (2009, background): “It remains controversial whether neurogenesis and migration of neuroblasts to the olfactory bulb continue in adult humans (Curtis et al. 2007, Sanai et al. 2007).”
Developmental regulation of human cortex transcription and its clinical relevance at base resolution (2014, neutral): “…of previously identified developmentally significant genes during fetal life, such as SOX11 (also shown in Figure 1) which encodes a transcription factor involved in the regulation of embryonic development 18 and DCX , which is involved in the migration and organization of neuroblasts 19 .”
BRAIN REGENERATION IN PHYSIOLOGY AND PATHOLOGY: THE IMMUNE SIGNATURE DRIVING THERAPEUTIC PLASTICITY OF NEURAL STEM CELLS (2011, background): “In the SVZ of the lateral ventricles, a region highly related to the embryonic SVZ (49), neurons are born and feed into a network of chains of tangentially migrating neuroblasts that travel along the so-called rostral migratory stream (RMS) to reach the olfactory bulb (FIG.”
Mechanisms and functional implications of adult neurogenesis. (2008, positive): “Neurogenesis also occurs in human brains in the SGZ and possibly the SVZ (Curtis et al., 2007; Eriksson et al., 1998; Sanai et al., 2004).”
Association of olfactory dysfunction with risk for future Parkinson's disease (2008, background): “The neural stem or precursor cells originate in the subventricular zone between the striatum and lateral ventricle, and migrate along the rostral migratory stream to the olfactory bulb where they mature into functioning interneurons.(37,38) Diminished olfactory neurogenesis in mice is associated wit”
Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration. (2014, methodology): “Based on the knowledge that polySia is a marker of adult neurogenesis in the rodent SVZ, immunostaining for polySia has been used to identify the presence of the SVZ/RMS system in rabbits (274, 373), non-human primates (165, 246, 365, 410), and humans (36, 101, 379, 404, 405, 540).”
Correlation between olfactory bulb volume and olfactory function (2008, positive): “Here, neuroblasts migrate along the rostral migratory stream and replace interneurons (periglomerular cells, granular cells) in the OB leaving the major relay neurons, mitral cells, substantially unaffected (Curtis et al., 2007).”
Adult Neurogenesis in Humans. (2015, background): “Curtis et al. (2007) reported an extension of the lateral ventricle that reaches the olfactory bulb with highly proliferative cells surrounding this hollow tube.”
Adult neurogenesis and the olfactory system. (2009, background): “This occurs in all species studied, including humans (Bedard and Parent, 2004; Curtis et al., 2007; Maresh et al., 2008).”