The Emotional Brain, Fear, and the Amygdala

By Joseph E LeDoux. Cellular and molecular neurobiology, 2003

1,829 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Cognitive Neuroscience, Social Psychology

View Paper: https://www.semanticscholar.org/paper/651694be9e5742fa9f49704390f1f42ea554d23c

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Citations in the corpus

A spatial judgement task to determine background emotional state in laboratory rats, Rattus norvegicus (2008, positive): “…emotion, animal welfare 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 The study of animal emotions is gaining increasing credence within the research community including psychology, neuroscience and behaviour (e.g. Rolls, 2000; LeDoux, 2003; Paul et al., 2005).”
Emotion and the motivational brain (2009, background): “Research with animals (e.g., Davis, 2000; Fanselow and Poulos, 2005; Kapp et al., 1994; LeDoux, 2003) has defined the key neural structures in this survival network (see Fig.”
The molecular and systems biology of memory. (2014, positive): “Implicit, Nondeclarative, Memory in Mammals Some of the strongest evidence linking learning to synaptic plasticity in the mammalian brain comes from experiments focused on implicitly learned fear (Davis et al., 1994; LeDoux, 2003, 1995).”
Neurocircuitry of Mood Disorders (2010, background): “The anatomical projections from the amygdala and mPFC to the hypothalamus, PAG, locus ceruleus, raphe, and autonomic-related brainstem nuclei play major roles in organizing the endocrine, autonomic, and behavioral responses to stressors and emotional stimuli (Figure 10) (Davis and Shi, 1999; LeDoux,”
Childhood Adversity and Neural Development: Deprivation and Threat as Distinct Dimensions of Early Experience (2014, background): “Fear is a defensive mechanism that activates behavioral and neurobiological responses to danger that promote survival, including freezing and activation of sympathetic nervous system and HPA axis, generating downstream hormonal and metabolic changes (LeDoux, 2003).”
Emotion Regulation and Stress (2011, background): “It plays a crucial role in processing, coordinating, and integrating of incoming sensory and cognitive information with emotional effect (LeDoux 2003).”
Whence Collective Rituals? A Cultural Selection Model of Ritualized Behavior (2006, background): “Its neural correlates are distinct from those of fear-systems that respond to actual danger (LeDoux 2003).”
Alcohol: Effects on Neurobehavioral Functions and the Brain (2007, background): “…of motivational significance of stimuli and to the mediation and control of major emotions such as love, fear, rage, anxiety, and general negative affective states (Aggleton 2000; Amaral et al. 2003; Breiter and Rosen 1999; Everitt et al. 2003; LeDoux 2003; Pitkänen et al. 2000; Rolls 2000).”
The Origins of Specific Phobias: Influential Theories and Current Perspectives (2009, background): “Projections from the amygdala to the brainstem are involved in the expression of fear responses, and projections from the amygdala to the cortex are believed to contribute to the experience of fear and other cognitive aspects of emotional processing (LeDoux, 2003; see also Barrett, Mesquita, Oschner”
Meditation states and traits: EEG, ERP, and neuroimaging studies. (2006, background): “In contrast, the nonreligious individuals reported experiencing a happy state in reciting the nursery rhyme, which was associated with left amygdala activation that was correlated with affective state (LeDoux, 2003; Morris et al., 1996; Phan, Wager, Taylor, & Liberzon, 2004).”
The Curvature Effect (2016, background): “…viewing angular shapes activates the bilateral amygdala (Bar & Neta, 2007; Larson, Aronoff, Sarinopoulos, & Zhu, 2009; Larson, Aronoff, & Stearns, 2007), which in addition to the processing of positive emotions is also involved in the processing of fear (Ledoux, 2003; Morris, Ohman, & Dolan, 1999).”
Functional Connectivity of the Human Amygdala using Resting State fMRI (2008, background): “…may result from greater negative intrinsic connectivity between the right CM subdivision and regions involved in fear learning (laterobasal nuclei) (LeDoux, 2003; Phelps and LeDoux, 2005) as well as the regulation of emotion (medial frontal gyrus) (Hariri et al., 2003; Irwin et al., 2004;…”
Beyond Rational Choice: the Hot/Cool Perspective of Criminal Decision Making (2013, background): “Evidence for this interaction comes from neuroscience as neural pathways run both from the more primitive brain sections associated with hot affective processing, such as the limbic system and the amygdala, to the prefrontal cortex, which is responsible for cool deliberative processing, and vice ver”